Ni ubuhe buryo bukwiye bwo kurwanya ubushyuhe?Menya "urwego rwumutekano" ukurikije ibisabwa.
Ubushyuhe bukwiye bwo guhangana nubushyuhe bwo hejuru - ubushyuhe, hejuru - filtri ikora neza ntabwo yashyizweho uko bishakiye; bigenwa nubushyuhe bukora nubushyuhe bwo guhindagurika kwifuru ya tunnel. Ihame ryingenzi ni "gupfukirana inzira ikabije mugihe usize umutekano muke."
1. Ibyingenzi Byibanze Kurwanya Ubushyuhe Hasi: dogere 180
Ubushyuhe ntarengwa bwo gutwika mu ziko rya farumasi ya farumasi ni dogere 180 (urugero, mugukumira kwumye kumacupa ya dosiye yo mu kanwa). Kubwibyo, akayunguruzo k'ubushyuhe bugomba kuba byibuze byibuze dogere 180 nta gutsindwa. Kuri ubu bushyuhe, ibiyungurura itangazamakuru, ibifata, hamwe na kadamu bigomba gukomeza imiterere itajegajega idafite ubushyuhe, guturika, cyangwa gusohoka.
2. Inzira isanzwe Ihuza: dogere 250-300
Amashyiga menshi ya tunnel mu bigo bitanga imiti yatewe inshinge akoresha uburyo bwa "dogere 250 x 30 minota" uburyo bwo kuboneza urubyaro (bujyanye nibisabwa na GMP kugirango bikoreshe ibikoresho bya aseptic). Bimwe murwego rwo hejuru - ibicuruzwa bishobora guteza akaga (nka biologiya) ndetse bikoresha uburyo bwa dogere 300 flash sterilisation. Kubwibyo, kubintu nkibi, birasabwa hejuru - ikora neza hamwe nubushyuhe bwa dogere 300 cyangwa irenga birasabwa kugirango hamenyekane neza ko kuyungurura bitagabanuka mugihe kirekire - igihe cyizuba - cyizuba (amasaha 8-12 yo gukora kumunsi).
3. Imipaka ikabije: Impamyabumenyi 350
Bimwe mubikorwa byihariye (nko gukuraho pyrogene yimbitse yo gukuramo liyofili) bisaba ubushyuhe burenze dogere 350. Muri ibi bihe, muyunguruzi igomba kuba yujuje ibisabwa kugirango ubushyuhe bwigihe gito bugere kuri dogere 350 hamwe nubushyuhe burambye bwa dogere 320. Byongeye kandi, ituze rigomba kugenzurwa hifashishijwe ibipimo byinshi byo hejuru - (Ikigereranyo kirenze cyangwa kingana na cycle 100).
Kurenga Ubushyuhe: Akayunguruzo '- Kurwanya Ubushyuhe
Hagati aho, kuzuza ibisabwa ubushyuhe ntibihagije. Akayunguruzo k'itanura ryumuti wumuti rigomba kugira imico itatu y "kurwanya ubushyuhe, isuku, no gutuza":
1. Akayunguruzo Ibikoresho: Fibre Fibre ni "Workhorse"
Ikirahure cya Fibre Fibre: Hamwe nubushyuhe bwa dogere 350-400, irerekana imiterere ihamye yimiti kandi ntisohora ihindagurika ryubushyuhe bwinshi, bigatuma ihitamo neza kubikorwa bikora hejuru ya dogere 300.
Gukomatanya Hejuru - Ubushyuhe - Kurwanya Akayunguruzo: Urugero, ibice bigize ibirahuri bya fibre na fibre ceramic birashobora kwihanganira ubushyuhe burenga dogere 400, ariko bigomba kwemeza ko nta kibazo cyo kumeneka fibre (kugirango wirinde kwanduza ibintu).
Ibikoresho bibujijwe: Ibikoresho bisanzwe bya polypropilene na polyester byungurura bifite ubushyuhe bwa dogere 80-120 gusa kandi bizashonga kandi bibore kubushyuhe bwinshi. Birabujijwe rwose gukoreshwa mu ziko ryumye.
2. Ibigize Imiterere: Kuraho "Hejuru - Ibyago by'ubushyuhe"
Ikadiri: Koresha 304/316 ibyuma bidafite ingese kugirango wirinde ingese nicyuma ion kurekura mubushyuhe bwinshi.
Ikidodo: Koresha ubushyuhe - ubushyuhe - bwirinda silicone reberi (kurwanya ubushyuhe burenze cyangwa bungana na dogere 300) aho gukoresha reberi isanzwe ya nitrile (kurwanya ubushyuhe butarenze cyangwa bingana na dogere 120) kugirango wirinde guturika no kumeneka mubushyuhe bwinshi.
Inkunga ya Mesh: Ibikoresho byicyuma bigomba kuvurwa passivation kugirango birinde ubushyuhe - okiside yubushyuhe hamwe no kubyara ibice.
3. Kubahiriza: Gutambutsa "Ibipimo bibiri" kugirango umenye umutekano
Imikorere ya Filtration: Igomba gutsinda EN 1822 ikizamini gisanzwe, hamwe na H13 ikora neza cyangwa irenga (Kurenza cyangwa bingana na 99.97% @ 0.3μm) kugirango hafatwe mikorobe zose nuduce duto.
Ubunyangamugayo: Nyuma yubushyuhe bwo hejuru -, hindura PAO / DEHS ubunyangamugayo hamwe nigipimo cyo kumeneka kiri munsi cyangwa kingana na 0.01%. Ibisubizo by'ibizamini bigomba kuba byujuje ibisabwa na GMP.
"Ingaruka Zihishe" zo Guhitamo Ubushyuhe Buke
Niba akayunguruzo k'ubushyuhe budakwiriye, ingaruka zishobora guhungabanya ubuziranenge bwibiyobyabwenge:
Ubushyuhe budahagije: Akayunguruzo kagabanuka na karubone ku bushyuhe bwinshi, bigatuma igabanuka rikabije mu kuyungurura. Microorganisme yo hanze cyangwa uduce duto dushobora kwinjira mu ziko no kwanduza ibintu.
Kurwanya ubushyuhe bukabije: Guhitamo buhumyi ultra - hejuru - muyunguruzi yubushyuhe (urugero, ukoresheje akayunguruzo ka dogere 400 mugihe ubushyuhe bwibikorwa nyirizina ari dogere 250) bizongera ibiciro byibikoresho (ultra - hejuru {{7} models urugero rwubushyuhe ruhenze inshuro 2-3 ugereranije nicyitegererezo gisanzwe) kandi bishobora no kuvamo ubukana bwumuriro mwinshi cyane.
Ihame ryingenzi ryo kumenya "ubushyuhe bukwiye" hejuru yubushyuhe bwo hejuru -, hejuru - muyunguruzi mu ziko rya farumasi ya farumasi ni ugukoresha ubushyuhe ntarengwa bwo gukora nkibipimo, wongeyeho 10% -20%. Urugero:
Impamyabumenyi ya dogere 250 → hitamo akayunguruzo karwanya dogere 300;
Impamyabumenyi ya dogere 300 → hitamo akayunguruzo hamwe na dogere 350 irwanya ubushyuhe.
Muri icyo gihe, hagomba gukorwa isuzuma ryuzuye rishingiye ku gushungura ibintu bifatika, kubahiriza imiterere, no gushyira mu gaciro. Gusa muri ubu buryo, ibikoresho byo gupakira imiti bishobora gukomeza umurongo wanyuma wo kurinda isuku ahantu habi h’ubushyuhe bwo hejuru -, bikuzuza rwose ibisabwa na GMP bikenewe kugirango habeho umusaruro w’imiti.